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Oxidative Stress
Oxidative stress is more important than acid in reflux oesophagitis – (08-23-01)
James Bogash
Oxidative stress is more important than acid in reflux oesophagitis
What a wonderful concept!! I cannot remember how many times I have had to explain to a near hostile listener in a group I’m speaking to that he or she has a very, very low likelihood of making too much stomach acid; in reality almost all of us make too little as we grow older. This article (which is a rat study) suggests that acid does not play the major role; rather, increased oxidative stress is the major player. This would suggest vitamin C, E, CoQ10 and other antioxidants may be more effective than acid-blockers for treatment of GERD.
Gut — Abstracts: Oh et al. 49 (3): 364
