Acute GI permeability responses to different NSAIDs This is one of those topics regarding NSAIDs that has such a potentially harmful impact on our systemic health and yet is never address and few patients are aware of it. Note that the dosages used in this study were not large and changes were seen within two […]
Celebrex Has No Safety Advantage Over NSAIDs, Panel Says Celebrex’s manufacturer’s are not going to like this. The new selective COX-2 inhibitors where designed to be safer on the stomach (don’t forget that NSAIDs can also damage the liver, kidneys, GI tract other than the stomach, as well as the joints themselves…). But post-marketing studies […]
Risk of birth defects and miscarriage in pregnant users of NSAIDs This study did not show an increase risk of birth defects w/ NSAID use, but did show an increase in the likelihood of a miscarriage. In many women unable to maintain a pregnancy, factors such as this, as well as homocysteine levels should be […]
NSAIDs and Persistent Pulmonary Hypertension of the Newborn This article points out yet another side effect of NSAIDs; potentially damaging effects on the fetus. It never ceases to amaze me that so many patients consider chiropractic dangerous and yet can not put NSAID use into perspective. This effect on the fetus is new to me, […]
Direct toxicity of NSAIDS for renal medullary cells Much attention has been focused on the gastrointestinal side effects of NSAIDs, but frequently the damaging effects on the liver, kidneys and joints are never mentioned. An article that appeared in the NEJM several years back gave a LIFETIME accumulation of effects from NSAIDs and acetominophen. 5000 […]
