NUTRITION AND ABERRANT DNA METHYLATION PATTERNS IN ATHEROSCLEROSIS: MORE THAN JUST HYPERHOMOCYSTEINEMIA?
I just love situations like this. Basically, mainstream medicine is just beginning to embrace the idea that maybe we should check homocysteine levels when evaluating for cardiac risk. And I have notice over the years that more and more people that attend my seminars are aware of homocysteine. Some still fight with their PCPs to get the test ordered. So here we are, now looking for factors that are even more fundamentally important than homocysteine.
The authors of this review acknowledge that elevated homocysteine coupled with inadequate levels of methylation factors (such as folic acid, B12, B6, SAMe…), but feel that there is yet a more basic alteration at the nutritional levels that occurs that makes the arteries more susceptible to damage from homocysteine. Stay tuned..