Effect of Metformin and Intensive Lifestyle Intervention on the Metabolic Syndrome
I’ve always said that, while metformin does indeed reduced insulin resistance, I strongly advocate lifestyle changes first and foremost. Metformin reduced incidence by 17%, lifestyle by a whopping 41%. So, lifestyle changes are much more effective and metformin carries significant risks of side effects. The side effects of lifestyle change? Lowered rates of diabetes, CVD, osteoporosis, osteoarthritis, cancer….