Tocopherols inhibit cyclooxygenase activity
Science has spent millions (if not billions) of dollars and many years to develop selective COX-2 inhibitors because the traditional nonselective COX inhibitors were too dangerous. And side effects of these drugs are starting to pop up…deaths and heart failure as a warmup…. But nature does make some very safe and VERY selective COX-2 inhibitors!! This article reviews a very specific type of nutrient, gamma tocopherol and its metabolite (tocopherol is Vit E…).
PNAS — Abstracts: Jiang et al. 97 (21): 11494