Immune mechanisms of allergen-specific sublingual immunotherapy
While still not well accepted by many physicians in this country, the research behind sublingual immunotherapy is growing. It’s safety is very high, and every study I’ve come across finds a benefit. Basically, the patient’s allergies are identified, and they are given a vial of liquid that they put under their tongue.
Most likely, this route gets down to the immune cells surrounding the gut (the GALT). The GALT then evaluates this small amount of allergen, kind of twisting it around in it’s little white blood cell hands, sees nothing threatening, and sends the signal of “no problem” to the rest of the immune system.
This works to tone down the allergic response to that particular substance. It is truly working on fixing the problem.