Lifespan Prolonged in Autoimmune-Prone Mice Fed Diet with Indole-3-Carbinol
This study brings up an important factor of one of today’s common medical practices. Indole-3-carbinol has been shown to lower risk of cancer by affecting the 2/16 hydroxylation ratio of estrogen at a genetic level.
This study adds the benefit of potential modulation of autoimmune conditions as well. I3C is found in cruciferous veggies such as broccoli, brussel sprouts and cauliflower. The catch? I3C is not the active form–it must be converted to diindolmethane by stomach acid. Might our obsession with shutting down acid production lead to increased rates of certain types of cancer?
nutrition.org — Abstracts: Auborn et al. 133 (11): 3610.