Apolipoprotein B and apolipoprotein A-I: risk indicators of coronary heart disease and targets for lipid-modifying therapy
Just when you thought you had it down–LDL cholesterol BAD, HDL cholesterol GOOD, we identify subfractions of both of these cholesterols. HDL has several subfractions, with HDL-2 believed to be the real player for lowering CVD risk.
This study confirms previous evidence that apo B increases risk and apo A-1 lowers risk. Once again, it’s almost a little comical and a little sad when most clinicians are still oblivious to the research and continue to use only cholesterol to stratify risk for CVD.