Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
I’ve continued to say that mitochondrial dysfunction is the root of all evil, and have yet to see any studies that convince me otherwise. This article finds that mitochondrial function is reduced by 60% IN THE CHILDREN of patients with insulin resistance. If this just isn’t the scariest thing that we can envision for successive generations, then I’d be hiding under the desk if something contained worse news. The children of insulin resistant patients are 60% less efficient at using energy, resulting in fat accumulation in their cells. If we do not get on the bandwagon against insulin resistance soon, several generations of our children will be paying the price in chronic diseases.