REACTIVE OXYGEN SPECIES ASSOCIATED WITH DIABETIC DAMAGES – (02-17-03)



Are Oxidative Stress-Activated Signaling Pathways Mediators of Insulin Resistance and ß-Cell Dysfunction?

This article finds that reactive oxygen species (i.e. free radicals) are a result of elevated glucose levels, and these ROS than damage DNA, proteins and lipids. This damage than starts a snowball effect killing off beta cells of the pancreas and leading to the damage we associate with diabetes. This would suggest that antioxidant supplementation (N-acetylcysteine, Vit E, Vit C, CoQ10…) would be important nutrients for any patient with impaired glucose tolerance or diabetes.

Diabetes — Abstracts: Evans et al. 52 (1): 1

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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