Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength
We already know that inflammation is a major risk factor for just about every chronic disease you can think of, but there are two that don’t quickly jump to mind: osteoporosis and age-related muscle loss (sarcopenia). I’m not sure what the evolutionary advantage is to this mechanism, but I would envision something along the lines of providing a rapid source of protein or calcium into the bloodstream for short term survival after injury or sustained physical exertion. Either way, our pro-inflammatory lifestyle may not be killing us right away, but they sure as heck are keeping the nursing homes full.