Platelet membrane fluidity and peroxynitrite levels in migraine patients during headache-free periods
Two things to mention here. First, we are seeing a sustained movement towards the concept that migraines, just like the seizures that clinicians are not yet willing to throw in the same category, is strongly related to oxidative stress and mitochondrial dysfunction.
This article adds more fuel to this concept by evaluating the peroxynitrate levels in migraine and headache patients in between attacks. Levels were elevated, indicating either that oxidative stress contributes directly to the headaches, or that the headaches induce oxidative stress that persists long after the headache.
Also, I personally feel that migraines are constantly over-diagnosed by doctors that don’t understand HA. They never touch the neck and so cannot possibly rule out problems coming from the neck. And, most likely a patient who has had HA for many years has several types of HA going on, and they all need to be addressed for full resolution to occur.