MECHANISM UNDERLYING OXIDATIVE STRESS – 05-01-05)



Mechanism underlying oxidative stress-mediated lipotoxicity

In a nutshell, the researchers in this study found that elevated triglycerides (as would be found in insulin resistance) get sucked up into the macrophages (a type of white blood cells), and once there, started to destroy the mitochondria of the cell resulting in cell death.  The death of a macrophage in the bloodstream can lead to the production of foam cells and subsequent plague in the arteries.

Interestingly, vit C, NAC and resveratrol protected the macrophages from this death.  So, to extrapolate into a living, breathing human, antioxidants protect the cells that produce plaquing in the arteries, resulting in less plaque.

Read entire article here

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







Email:



Posted on
Category: Insulin
Disclosure of Material Connection: Some of the links in the post above are “affiliate links.” This means if you click on the link and purchase the item, I will receive an affiliate commission. Regardless, I only recommend products or services I use personally and believe will add value to my readers. I am disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: “Guides Concerning the Use of Endorsements and Testimonials in Advertising.”