Influence of oxLDL on the Viability of Osteoblastic Cells
While much hoopla has been generated about the links between LDL cholesterol levels and heart disease, in reality the association is thin. However, once LDL gets damaged and becomes oxidized (oxLDL), the links to heart disease now become much stronger. Of course, much like every other chronic disease, there are many metabolic abnormalities in common between disease states. If you’re at risk for one, you’re at risk for them all. Great news, huh?
In this study, researchers found an association between oxLDL levels and the health of the cells that create bone, thus connecting one link between CVD and osteoporosis. Again makes you question the logic of using a single drug to impact one single pathway of a chronic disease (i.e. anti-resporptive agents for osteoprosis, statins for cholesterol).