INSULIN RESISTANCE RESULTS IN HIGH BLOOD PRESSURE – (09-01-03)



Endothelial Dysfunction Induced by Hyperhomocyst(e)inemia–Role of Asymmetric Dimethylarginine

We’ve come across asymmetrical dimethylarginine (ADMA) previously. Basically, nitric oxide is a small molecule that has many functions, one of which is dilation of blood vessels to increase blood flow (ala nitroglycerin tablets, Viagra…). ADMA is nitric oxide’s arch enemy–the more ADMA, the less effective nitric oxide can be.

We are finding that insulin resistance disables the enzyme that breads down ADMA, effectively raising levels of ADMA and inhibiting nitric oxide vasodilation. The result?? High blood pressure.

Circulation — Abstracts: Stühlinger et al. 108 (8): 933

Read entire article here

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Insulin
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