INSULIN RESISTANCE AND INFLAMMATION CAUSE OF EACH OTHER – (10-15-03)



TNF-alpha Inhibits Insulin’s Stimulating Effect on Glucose Uptake and Endothelium-Dependent Vasodilation

In English, TNF-alpha, an intracellular messenger that up-regulates many aspects of the immune system, can increase insulin resistance. This issue, to me, is beginning to look like the chicken-and-egg problem. Does insulin resistance increase overall inflammation by increasing TNF-alpha levels, or is insulin resistance caused by underlying inflammation?? Most likely the answer lies somewhere in between.

Circulation — Abstracts: Rask-Madsen et al. 108 (15): 1815

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Categories: Inflammation, Insulin
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