Potential markers of oxidative stress in stroke
This is such an important concept to get a grip on. Sure, we can homogenized our patient’s brains in a blender and directly measure markers of oxidative stress, but patients rarely benefit from this approach.
It does appear from several studies that malondialdehyde (MDA) is turning out to be a good marker. This is nice, because there are already several cheap and easy urine tests to determine qualitatively MDA levels.
Once we get a complete picture of how effective these markers for oxidative stress are in the nervous system, we can begin to take a more aggressive stance on targeted antioxidant therapies to lower risk/progression of neurodegenerative disorders and stroke.