Fatness at birth predicts adult susceptibility to ovarian suppression: An empirical test of the Predictive Adaptive Response hypothesis
I can honestly say that I do not routinely ask patients about their birth status (premature, weight, weight gain in the first 6 months…) but given the increasing evidence for gestational events to preprogram the fetus, this is not an unrealistic route to take.
In this study, the authors found that, when pregnant women were well fed, their adult daughters had higher estrogen levels and these levels were harder to reduce with exercise. That would equate to a greater risk of breast and endometrial cancers. Wow!! Talk about needing to stratify responders in an “exercise to reduce breast cancer” epidemiological study!!