HIGH-DOSAGE VITAMIN E SUPPLEMENTATION MAY INCREASE ALL-CAUSE MORTALITY
My, wasn’t this one a hot one for a day or so? This always brings up the question about how some of these articles manage to make it to the mainstream media when other topics much more important (like Syndrome X) remain unheard of. A couple comments. First, the end results from the study were very weakly positive. 1.04 X risk. 1.00 risk means no effect, so a .04 increase in risk is very small.
Also, the “p” value is .035–this is an evaluation of how much the study results are a result of chance (p value of coin flip is 1). The lower the number the stronger the study. I prefer p values lower than .001. That being said, there’s still the possiblity of a risk, which is NOTHING NEW. I’ve included a strong article that reviews the pro-oxidant effects of Vit E. Vit E can act as a pro-oxidant but THIS IS ABOLISHED BY CO-ANTIOXIDANTS LIKE VIT C. From a natural perspective, we don’t treat supplements in a vacuum and lifestyle changes would ALWAYS be done in a package, not with just one supplement. I’m sure that taking Vit E along with Vit C and other compounds like green tea and red wine will show nothing but a strongly protective effect.
Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality — Miller et al., — Annals of Internal –