Fiber Down-Regulates Colonic TNF alpha and Nitric Oxide Production
While this is a rat study, it does show the potential for fiber to have an anti-inflammatory effect via the production of short chain fatty acids (which require presence of beneficial bacteria for the conversion). TNF alpha was one of the regulators that was studied. Remember that the hot new drug for Crohn’s and RA is a TNF-alpha blockade. It is very feasible that soluble fiber could show a similar benefit to this drug without the side effects and possibly additional benefits such as lowering colon cancer risk.
Nutrition.org — Abstracts: Rodríguez-Cabezas et al. 132 (11): 3263