Licorice Ethanolic Extract with PPAR-gamma Ligand-Binding Activity Affects Diabetes, Abdominal Obesity and Hypertension
This animal study gives results of the effects of licorice on the orphan nuclear receptor (so named because we previously were not sure what these genes did when they were turned on) PPAR-gamma. Keep in mind that we are only beginning to understand what these genetic receptors due, but we do know that they are a foundation upon which many aspects of our health (and disease) are built, so any compound affecting these receptors has the ability to impact several disease states. Conjugated linoleic acid and omega-3 fatty acids also affect these receptors. As a side note, this is not the sugar-laden licorice we find in today’s licorice ropes–this is the real stuff.
nutrition.org — Abstracts: Mae et al. 133 (11): 3369.