A few things to think about here. We could argue that healthy mitochondrial function is the Holy Grail of good health and longevity. Anything that improves mitochondrial function is a good thing. So, what does this mean if we focus so heavily in mainstream medicine on achieving good blood sugar control, but that this control does not change mitochondrial function?
Could it mean we’re barking up the wrong physiological pathway? I could rant and rave about surrogate end markers, but I’m sure you’ve read it from me before… It boils down to the cold, hard, undeniable fact that the ONLY way to properly manage chronic conditions like diabetes is through lifestyle changes. There is massive evidence that changing a particular number artificially through the use of drugs is not only not helpful, but dangerous.