BRAIN DAMAGE OCCURS DESPITE SUCCESSFUL DRUG TREATMENT IN EPILEPSY AND MIGRAINES. One of my continuing frustrations in our treatment of seizures (this includes true migraines) is that we view the treatement as successful if the seizures or migraines have stopped. The reality is all we’ve done is dumbed down the brain cells’ ability to communicate with one another, but have not improved the health of the neurons. In many cases it is quite the opposite.
This study adds weight to this idea in finding that treatment with one AED (Depakote) actually stopped the brain’s ability to recover from insult (plasticity) and promoted cognitive loss.