DO CLINICAL TRIALS HAVE ANY EFFECT ON HEART DISEASE?



Heart disease and clinical trials. It’s very common to use something called “surrogate endpoints” in drug trials. Basically, if a marker like cholesterol gets better w/ a drug, then we MUST be having an effect on heart disease, right?

Unfotunately, the answer is usually a big no. But it does make the drug look effective to doctors who don’t read medical research. In this review, the surrogate endpoint of plaque in the coronary arteries (which is used commonly w/ statin drug trials) was shown to have no impact in rates of cardiac events.

Read entire article here

 

James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Heart Disease
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