Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin – (12-31-01)

Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin

This study finds that taking NSAIDs (specifically ibuprofen) and aspirin together can lower the potential blood thinning effects of aspirin. Considering that these two drugs are frequently taken together this does cause some concern. However, I still question the use of aspirin for both primary and secondary cardioprevention. Studies do indicate that risk of heart attacks may drop, but risk of stroke increases. I guess you need to decide which you would prefer. Personally, I would focus on some of the 10 or so other lifestyle factors that can lower risk of heart attack without increasing risk of other diseases.

NEJM — Abstracts: Catella-Lawson et al. 345 (25): 1809

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.