CLA Causes Isomer-Dependent Oxidative Stress and Elevated CRP
Before you run for your biochemistry book, let me give you a quick refresher. Conjugated linoleic acid has two main forms: t10c12 and t9c11. These are pretty evenly mixed in most commercial preparations of CLA. However, negative side effects such as fatty liver have been observed with its use. This study and others point the finger at the t10c12 isomer as the main culprit. What does this mean? Nothing right now, but keep an eye out for preparations with only the t9c11 isomer in the future.
Circulation — Abstracts: Risérus et al. 106 (15): 1925