Butyrate, cytokines and intestinal epithelial cells
Butyrate is one of the short chain fatty acids produced when beneficial bacteria digest soluble fiber in the gut. Much research has supported the beneficial effects of butyrate on colonocytes. These benefits include stabilization of intestinal permeability, increased colonocyte differentiation (= lowered risk of cancer) and now anti inflammatory effects. The combination of probiotics and soluble fiber should be a first line approach for any GI problems.
Synergy : European Journal of Clinical Investigation 31 (12), 1060-1063