Antioxidant Î±-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kappaB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-ÎºB ligand and tumor necrosis factor-alpha
I admit it. I’ve got a thing for long, technical titles. Our view of osteoporosis is changing dramatically (at least in the research) and inflammation plays a major role in this. Basically, the more the inflammation, the higher number of cells that break down bone. Too many osteoclasts breaking down bone in comparison to osteoblasts buidling bone, and you lose bone too quickly. So anything that lowers inflammation will have a positive effect on bone.
So, this article looked at the ability of alpha lipoic acid to reduce oxidative stress and reduce the number of osteoclasts.