BONE LOSS MAY LEAD TO INCREASED RELEASE OF SUBSTANCE P AND TNF-ALPHA – (01-14-04)



Bone Loss Induced by Magnesium Reduction to 10% of Nutrient Requirement in Rats Associated with Increased Release of Substance P and TNF-alpha

Sorry for the long title, but there are two lessons here. First, osteroporosis, despite what you may believe from the dairy advertising, is not all about calcium. There are many other factors such as Vit D and magnesium that go into bone health. It is a disease of lifestyle and magnesium depletion may be one facet that osteoporotic patients are affected by. Second, magnesium deficiency resulted in up regulation of the immune system via TNF-alpha. So, you can take from this that magnesium may help lower overall inflammatory burden, or you can see how inflammation also plays a role in osteoporosis just like every other chronic disease it partakes in…

Nutrition.org — Abstracts: Rude et al. 134 (1): 79 –

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James Bogash

For more than a decade, Dr. Bogash has stayed current with the medical literature as it relates to physiology, disease prevention and disease management. He uses his knowledge to educate patients, the community and cyberspace on the best way to avoid and / or manage chronic diseases using lifestyle and targeted supplementation.







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Category: Osteoporosis Cures and Bone Health
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