Antidepressant drug trials exclude most “real” patients
This is an interesting article that dissects clinical trials for antidepressants. The authors find that most clinical trials do not match real life patients, and that, based on the patients in clinical trials, only about 15% of patients currently on antidepressants fit classification from the studies. I see many patients on antidepressants and many have jumped from drug to drug with only moderate results and many side effects. Too often these patients have not tried safer, more effective methods such as exercise and improving their diet.