The Holy Grail of Aging: Overview of the Mitochondria

THE HOLY GRAIL OF HEALTH?? For those of you who didn’t sleep through high school biology class, you’ll probably remember the mitochondria.  The powerhouse of the cell.  The site of ATP generation.  Well, fast forward 30 years and our understanding has blossomed.  It is well researched that the beginning of ALL chronic diseases begin with […]

Oxidative Capacity, Lipotoxicity, Mitochondrial Damage in Type 2 Diabetes – (07-02-04)

Oxidative Capacity, Lipotoxicity, Mitochondrial Damage in Type 2 Diabetes It’s always nice to have articles validating a multi-pronged approach to treating chronic diseases. While paying attention to the glycemic indices of a diet, it is also important to provide a multitude of compounds from foods that lower oxidative stress. In this review, oxidative stress was […]

ROLE OF MITOCHONDRIAL DYSFUNCTION IN INSULIN RESISTANCE – (05-29-03)

Mitochondrial dysfunction in elderly: possible role in insulin resistance. This is an interesting concept and would lead to some additional intervention for lower insulin resistance in an elderly population. Mitochondrial support with supplements such as coenzyme Q10, carnitine and malic acid may be warranted in this situation. This would, of course, be on top of […]

MITOCHONDRIAL DYSFUNCTION LEAD TO PARKINSON’S DISEASE – (12-09-04)

XENOBIOTIC METABOLISM IN PARKINSON’S DISEASE I would have to say that we have PD pretty close to wrapped up. There has been strong evidence of mitochondrial dysfunction leading to loss of dopaminergic neurons leading to the symptoms of PD. Once that is understood, all the protective factors and the contributing factors really make sense. This […]

OXIDATIVE STRESS AND INFLAMMATION LEAD TO MITOCHONDRIAL DYSFUNCTION – (08-11-04)

No evidence for heritability of Parkinson disease in Swedish twins. I know when I speak in the community on neurodegenerative conditions like Parkinson’s and Alzheimer’s, there is usually surprise and quite a bit of resistance when I describe them as diseases of lifestyle. However, the research is pointing more and more towards (sound familiar??) oxidative […]