August 21, 2000 Research Update

Gastric mucus synthesis inhibited by cigarette smoke

Not that anyone should need any additional reasons, but this research studies may explain how smoking can increase your risk of gastric ulcers. Gut -- Abstracts: Ma et al. 47 (2): 170 http://gut.bmjjournals.com/cgi/content/abstract/47/2/170

Effect of proinflammatory interleukins on jejunal nutrient transport

This study indicates that, with systemic inflammation, more nutrients are absorbed. This would correspond well with the increased need for certain nutrients under times of stress. However, it would seem logical to extrapolate that, with prolonged inflammation, the intestines become too permeable and larger molecules can cross into the body that are not supposed to be there. Gut -- Abstracts: Hardin et al. 47 (2): 184 http://gut.bmjjournals.com/cgi/content/abstract/47/2/184

Habitual snoring and obesity in the development of diabetes

We have long viewed snoring as a benign condition, and yet recent research is starting to link snoring with many chronic diseases.

Journal of Internal Medicine 248 (1), 13-20 There are many similarities between diabetes (mainly type 2) and sleep breathing disturbances regarding risk factors, anthropometric criteria and consequences of morbidity and mortality. The aim of this study was to investigate whether the association between habitual snoring and diabetes is entirely dependent on obesity. We conclude that, in males aged 30–69 years, habitual snoring is associated with an increased incidence of diabetes within 10 years. Although obesity is the main risk factor for developing diabetes, coexistent habitual snoring may add to this hazard.

TNF in type 1 diabetics and glucose control and cardiovascular risk

This study points to TNF-alpha as a contributor to the damage done to the pancreas in Type I diabetes. Recall that TNF inhibitors are the new rheumatoid arthritis and now Crohn's disease drugs. As research gets more and more specific, I truly believe that we will come to find really only a few abnormalities causing most of man's chronic diseases. TNF-alpha is a perfect example.

Journal of Internal Medicine 248 (1), 67-76 The cytokine TNF-a reveals a complex relationship with diabetes. It is involved in beta-cell damage leading to type 1 diabetes, causes insulin resistance associated with obesity and is of influence in the formation of atherosclerotic vascular lesions. We were interested in the possible association of this cytokine with metabolic control and cardiovascular risk factors in patients with type 1 diabetes. Our data indicate that TNF-a plasma levels are increased in type 1 diabetes mellitus and reveal a significant association with metabolic long-term control parameters, HbA1c and fructosamine for glycaemic control, and HDL cholesterol for triglyceride metabolism, as well with lipid peroxidation.

Mandibular and Head-Neck Movements During Jaw Activities

This articles helps justify the many positive results that chiropractors experience in treating TMD and jaw pain.

J Dent Res 2000 Jun;79(6):1378-84 The results support the idea of a functional relationship between the temporomandibular and the cranio-cervical neuromuscular systems. We therefore suggest a new concept for human jaw function, in which "functional jaw movements" are the result of activation of jaw as well as neck muscles, leading to simultaneous movements in the temporomandibular, atlanto-occipital, and cervical spine joints.

Quick Manual Treatment in Whiplash is Best

Ask any chiropractor and they could have saved alot of money on this research project. As with any injury, the longer treatment is delayed the less likelihood of a good outcome.

Spine 2000 Jul 15;25(14):1782-1787 In patients with whiplash-associated disorders caused by a motor vehicle collision treatment with frequently repeated active submaximal movements combined with mechanical diagnosis and therapy is more effective in reducing pain than a standard program of initial rest, recommended use of a soft collar, and gradual self-mobilization. This therapy could be performed as home exercises initiated and supported by a physiotherapist.