Lifecare Chiropractic
James Bogash, D.C.
1830 S. Alma School Rd
Bldg 7, Ste 135
Mesa, AZ 85210
(480) 839-CARE (2273)
***Glucose ingestion induces an increase in intranuclear nuclear factor κB, a fall in cellular inhibitor κB, and an increase in tumor necrosis factor α messenger RNA by mononuclear cells***
Hate to start off an Update with a title like that, but... One thing people may not realize is that the mere act of eating is an inflammatory process. Our best bet is to eat a diet loaded with phytonutrients to mitigate this inflammation. This article just further confirms this process and looks at glucose's ability to turn on the entire inflammatory cascade. Compare this with the ingestion of refined carbs--all the sugar with no phytonutrients.
***Association Between Serum 25(OH)D Concentrations and Bone Stress Fractures in Finnish Young Men***
I think the most interesting thing in this study was the OR--lower serum Vit D levels led to an increase in risk for stress fractures by 3.6 times. And in a relatively young population that we would not normally think of bone health/Vit D as being of concern. So add Vit D supplementation to any patients that have stress fractures and shin splints that just won't heal from anything else.
***Low-Level, High-Frequency Mechanical Signals Enhance Musculoskeletal Development of Young Women With Low BMD***
Our office, since this article triggered an interest in Whole Body Vibration, has since purchased one of the higher-end WBV units. The research behind this therapy is intriguing, but probably the strongest is in the region of increasing bone density, to the point where some researchers have suggested using this therapy in teens to build their bone mass as high as possible to lower the risk of osteoporosis decades later.
***Effects of Extended-Release Niacin on Lipoprotein Particle Size, Distribution, and Inflammatory Markers in Patients With Coronary Artery Disease***
While niacin has been known for a long time to be one of the few compounds used in a pharmacologic manner (soy, flax and exercise does as well--but these aren't use in a pharmcologic approach), the beneficial subclass changes in the specific lipids in this study were quite surprising. Recall that we have further delved into the HDL and LDL molecules and found that these particles can be furthered subdivided, and that these subclasses can have even more dramatic abilities to predict heart disease risk. Niacin in this study was found to raise the "best of the best" as large particle HDL by 32% and reduced the small particle LDL by 12% while also raising the large particle LDL by 82%. Taken together, these changes would suggest that niacin has a much greater ability to lower CVD risk than many other molecules available.
***Obese Children and Adolescents--A Risk Group for Low Vitamin B12 Concentration***
As if obese kids didn't have the deck stacked against them already. I guess the important question may be how are these kids deficient? Vit B12 is readily available in an animal-based diet, so why would this population, which is much more likely to eat animal based rather than plant based, be deficient? I am unsure why B12 would be deficient in this age group. In seniors and stressful persons, we can look to digestive deficiencies that impair our absorption of B12 and this is relatively common.
***Low serum concentrations of 25-hydroxyvitamin D in older persons and the risk of nursing home admission***
Wow!! 3.5 times the risk for nursing home admission in Vit D deficient patients. Skip the long term care insurance and buy some supplemental Vit D... But seriously, if something as simple, cheap and safe as Vit D supplementation can drastically reduce the number of nursing home admissions, than articles like this one need to be plasted all over the news. With all the research on Vit D and the large range of strong benefits, Vit D supplementation in the range of 2,000 IU/day needs to be moving in the direction of a national recommendation.
***Thiazolidinedione Use and Bone Loss in Older Diabetic Adults***
Avandia and Actose are a class of diabetic drugs known as TZDs that act on the PPAR gamma receptor. Unfortunately, like every other drug out there, they have some long lists of side effects. This particular study looks at the bone damaging effect of these drugs. Interestingly, while sticking with the near-Vitamin-D-worship status of this Updates, Vit D not only protects bones but also helps manage insulin resitance, a precursor to diabetes. You can also add exercise to that list as well. So basically, the approaches we should be taking that involve diet and lifestyle will lower the risk of diabetes while protecting the bones. This class of drugs, however, actually contributes to more bone loss the longer you're on them. Would SEEM like a no-brainer, huh?
***Combined high-resolution magnetic resonance imaging and histological examination to explore the role of ligaments and tendons in the phenotypic expression of early hand osteoarthritis***
As a chiropractor that has a strong focus on the soft tissue component of musculoskeletal health, I found this article rather intriguing. Basically, whenever they looked at arthritis in the small joints of the hand, those areas that had ligaments with pathological changes (basically scar tissue and thickening) had more arthritis. While no one study confirms anything, this articles does lend support to those physicians focusing much more strongly on how much the soft tissues contribute to long term joint health.
***Maternal Supplement, Micronutrient, and Cured Meat Intake during Pregnancy and Risk of Medulloblastoma during Childhood: A Children's Oncology Group Study***
While this is a very unfair situation and I am not casting blame in any one parents' direction, I do strongly blame society for believing that childhood cancers are a "luck of the draw" scenario that we have little control over. I have always strongly believed that the enivronment in the womb does a huge amount of programming of that infant for the decades to come, and this article further supports that. It also should be some type of impetus to get doctors away from those poor quality pharmaceutical prenatal vitamins that just barely provide enough folic acid and iron to address the anemia and neural tube defect issues but nothing else of substance.
***Vitamin D Intake and the Risk for Pancreatic Cancer in Two Cohort Studies***
Aw heck...I thought I'd begin and end this Update with more info on the importance of Vit D. And to add hear--pancreatic cancer is a great killer. We just don't get 5 year survival rates with pancreatic cancer. With all the research showing strong protection of Vit D on several types of cancer, I am waiting for the American Cancer Society to come out with recommendations to increase Vit D intake. They wouldn't even notice this drop in the bucket for prevntion within that massive budget devoted to "finding a cure...."
Dr. James Bogash, D.C.
1830 S. Alma School Rd, Bldg 7, Ste 135, Mesa, AZ 85210
(Alma School Road, just south of the Superstition Freeway/Highway 60)
Chiropractic Health Care for Chandler, Mesa and Tempe Arizona
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